<p>Gastric H⁺/K⁺-ATPase Expression in Normal Laryngeal Tissue and Laryngeal Carcinoma</p>

Cyclin D1 Expression in Patients with Laryngeal Squamous Cell Carcinoma

Background & Objective: Laryngeal squamous cell carcinoma (LSCC) is considered to be one of the most common cancers of the head and neck, accounting for roughly 90% of all malignant tumors of the larynx. To have a timely diagnosis for a better and practical therapy, molecular markers have to be investigated. The aim of this study was to determine the expression of Cyclin D1 (CD...

Neurotrophin expression and laryngeal muscle pathophysiology in response to recurrent laryngeal nerve-crush injury

Laryngeal palsy often results from recurrent laryngeal or vagal nerve injury during oncologic surgery of the head and neck. The aim of this study was to describe the characters of spontaneous reinnervation in rats following recurrent laryngeal nerve (RLN) crush injury. Twenty-five male Sprague-Dawley rats each were subjected to a 5-mmlong crush injury to the right recurrent laryngeal nerve. Voc...

Stem Cell‐Based Tissue‐Engineered Laryngeal Replacement

: Patients with laryngeal disorders may have severe morbidity relating to swallowing, vocalization, and respiratory function, for which conventional therapies are suboptimal. A tissue-engineered approach would aim to restore the vocal folds and maintain respiratory function while limiting the extent of scarring in the regenerated tissue. Under Good Laboratory Practice conditions, we decellulari...

Isolated Laryngeal Amyloidosis

Neurotrophin expression and laryngeal muscle pathophysiology following recurrent laryngeal nerve transection

Laryngeal palsy often occurs as a result of recurrent laryngeal or vagal nerve injury during oncological surgery of the head and neck, affecting quality of life and increasing economic burden. Reinnervation following recurrent laryngeal nerve (RLN) injury is difficult despite development of techniques, such as neural anastomosis, nerve grafting and creation of a laryngeal muscle pedicle. In the...